Melatonin: Clinical Perspectives and Pharmaceutical Applications

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Melatonin is a hormone that is associated with the control of sleep-wake cycle and is primarily secreted by the pineal gland at night. It is also taken orally as a dietary supplement to treat short-term insomnia such as from shift work or jet lag. Some melatonin receptor agonists are also available as medications that work as melatonin but may have some adverse effects for sleep conditions. Side-effects of melatonin use are headaches, somnolence, diarrhea, nausea, nervousness, irritability, abnormal dreams, psychomotor hypersensitivity, mouth ulcers, chest pain, mood swings, etc. These side-ef...

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